Hyperbilirubinemia during Atazanavir Treatment in 2,404 Patients in the Italian Atazanavir Expanded Access Program and MASTER Cohorts

@article{Torti2008HyperbilirubinemiaDA,
  title={Hyperbilirubinemia during Atazanavir Treatment in 2,404 Patients in the Italian Atazanavir Expanded Access Program and MASTER Cohorts},
  author={Carlo Torti and Giuseppe Lapadula and Andrea Antinori and T. R. Quirino and Renato Maserati and Filippo Castelnuovo and Franco Maggiolo and Andrea De Luca and Giuseppe Paraninfo and Francesco Antonucci and Guglielmo Marco Migliorino and Adriano Lazzarin and Giovanni di Perri and Giuliano Rizzardini and R. Esposito and Giampiero Carosi},
  journal={Infection},
  year={2008},
  volume={37},
  pages={244-249}
}
Although the mechanism of atazanavir (ATV)-related hyperbilirubinemia is well identified, its prevalence, risk factors, and association with transaminase flares have rarely been assessed in a large population from the “real life” setting. Prospectively collected data on 2,404 patients from the Italian MASTER Cohort and the Italian ATV expanded access program database were examined. Uni- and multivariable Cox proportional hazards regression models were conducted to identify risk factors for… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

Xenobiotica; the fate of foreign compounds in biological systems • 2014
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Hyperbilirubinemia among Patients in the HIV Outpatient Study (HOPS) receiving atazanavir (abstract TuPe2 1B02)

D Ward, J Curtin, J Richardson
Rio de Janeiro: 3rd International AIDS Conference on HIV Pathogenesis and Treatment, • 2005

Atazanavir: new option for treatment of HIV infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2004

Similar Papers

Loading similar papers…