Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled clinical trial.

@article{Bouachour1996HyperbaricOT,
  title={Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled clinical trial.},
  author={Gilles Bouachour and Patrick Cronier and J. P. Gouello and Julien Toulemonde and Abdelhafid Talha and Philippe Alquier},
  journal={The Journal of trauma},
  year={1996},
  volume={41 2},
  pages={
          333-9
        }
}
Hyperbaric Oxygen (HBO) therapy is advocated for the treatment of severe trauma of the limbs in association with surgery because of its effects on peripheral oxygen transport, muscular ischemic necrosis, compartment syndrome, and infection prevention. [] Key Method Thirty-six patients with crush injuries were assigned in a blinded randomized fashion, within 24 hours after surgery, to treatment with HBO (session of 100% O2 at 2.5 atmosphere absolute (ata) for 90 minutes, twice daily, over 6 days) or placebo…
Adjuvant Hyperbaric Oxygen Therapy in the Management of Crush Injury and Traumatic Ischemia: An Evidence-Based Approach
TLDR
A systematic review of the literature concluded that adjunctive HBO is not likely to be harmful and could be beneficial if administered early and well designed clinical studies are warranted.
HYPERBARIC OXYGEN THERAPY IN THE MANAGEMENT OF CARBON MONOXIDE POISONING, OSTEORADIONECROSIS, BURNS, SKIN GRAFTS, AND CRUSH INJURY
  • P. J. Saunders
  • Medicine
    International Journal of Technology Assessment in Health Care
  • 2003
TLDR
Although hyperbaric oxygen therapy is clearly appropriate in the treatment of decompression sickness and air/gas embolism, there is no convincing evidence of effectiveness for the conditions reviewed, despite its widespread use.
Hyperbaric Oxygen in Lower Limb Trauma (HOLLT); protocol for a randomised controlled trial
TLDR
The question of whether hyperbaric oxygen therapy can significantly improve outcomes in severe lower limb trauma is answered and will make a significant contribution to the trauma literature.
Recent Advances in Hyperbaric Oxygen Therapy
TLDR
Hyperbaric Medicine has found a distinct role in the modern era of evidence-based medicine and there is recently a renewed interest in this field all over the world.
Hyperbaric oxygen therapy: types of injury and number of sessions--a review of 1506 cases.
TLDR
Clinical data indicative of the number of hyperbaric oxygen therapy HBO2 sessions that should be prescribed for adjuvant treatment of tissue injuries of differing severity seem to support the initial indication of 15 HBO 2 sessions for the treatment acute injuries, and 30 for treatment of chronic injuries.
Can preventive hyperbaric oxygen therapy optimise surgical outcome?: A systematic review of randomised controlled trials.
TLDR
Peri-operative preventive HBOT may be a promising intervention to improve surgical patient outcome, however, future work should consider addressing the methodological weaknesses identified in this review.
Hyperbaric Oxygen in the Treatment of Acute Muscle Stretch Injuries
TLDR
It is suggested that hyperbaric oxygen therapy may play a role in accelerating recovery after acute muscle stretch injury and further studies are needed before definitive conclusions and treatment recommendations can be made.
Double-blind trials in hyperbaric medicine: A narrative review on past experiences and considerations in designing sham hyperbaric treatment
TLDR
Using a lower pressure than the hyperbaric oxygen group while breathing 21% oxygen best matches the inertness of the placebo, and although studies show that use of a lower Pressure does allow adequate blinding, this is associated with more practical issues than with the other strategies.
[The effects of hyperbaric oxygen and surgical decompression in experimental compartment syndrome].
TLDR
Adjuvant HBO is beneficial in the treatment of compartment syndrome because the findings of inflammation and necrosis were less in the HBO group when compared with the fasciotom and HBO-fasciotomy groups.
Efficacy of Hyperbaric Oxygen Therapy on Second Degree of Burn Wound of Forearm
TLDR
HBOT seems effective in accelerating the healing rate and shortening of hospitalization time on second degree bum wound of the forearm, reflecting efficacy of HBOT in healing process.
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