Hyperbaric oxygen therapy for stroke: a systematic review of the evidence

@article{Carson2005HyperbaricOT,
  title={Hyperbaric oxygen therapy for stroke: a systematic review of the evidence},
  author={Susan M. Carson and Marian S. McDonagh and Barry Russman and Mark Helfand},
  journal={Clinical Rehabilitation},
  year={2005},
  volume={19},
  pages={819 - 833}
}
Objective: To identify the benefits and harms of using hyperbaric oxygen therapy to treat acute or subacute stroke or the chronic effects of a stroke. We aimed to identify any gaps in the evidence to provide guidance for future research. Design: A systematic review of the evidence. Search strategy: We searched MEDLINE, EMBASE, the Cochrane Library, HealthSTAR, CINAHL, MANTIS, bibliographic databases from professional societies and hyperbaric oxygen therapy practitioners, and reference lists… 

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References

SHOWING 1-10 OF 40 REFERENCES
Hyperbaric Oxygen Therapy in Acute Ischemic Stroke: Results of the Hyperbaric Oxygen in Acute Ischemic Stroke Trial Pilot Study
TLDR
Although the HBO protocol appears feasible and safe, it does not appear to be beneficial and may be harmful in patients with acute ischemic stroke.
Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study.
TLDR
It is hypothesized that HBO might improve outcome after stroke, as it detected an outcome trend favoring HBO therapy and a large randomized trial might be required to address the efficacy of this therapy.
A pilot study of hyperbaric oxygen in the treatment of human stroke.
TLDR
The study was interrupted when it noticed what appeared to be a trend favoring the air-treated patients, whose neurological deficits were less severe and whose infarcts were smaller, and was probably an artifact of the randomization process.
Hyperbaric oxygen therapy for brain injury, cerebral palsy, and stroke.
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The Use of Hyperbaric Oxygenation in the Treatment of Cerebral Ischemia and Infarction
TLDR
Hyperbaric oxygenation may provide supportive therapy in some patients with acute cerebral ischemia, thereby permitting the removal of the occlusive lesion by surgery or other methods, and indicate that inSome patients neuronal structures remain viable for some hours after loss of function in acute cerebral waschemia.
Hyperbaric Oxygenation as an Adjunct Therapy in Strokes Due to Thrombosis: A Review of 122 Patients
TLDR
HBO is used as adjunctive treatment and there appears to be justification for a controlled study to delineate the treatment further, and it is essential to treat patients with stroke at 1.5 to 2 atmospheres absolute (ATA).
Identification of Hypometabolic Areas in the Brain Using Brain Imaging and Hyperbaric Oxygen
TLDR
The data support the hypothesis that idling neurons and ischemic penumbras, when given sufficient oxygen, are capable of reactivation and changes in tracer distribution after a single exposure to HBOT may be a good prognostic indicator of viable neurons.
Rehabilitation of persons with traumatic brain injury.
TLDR
This statement provides state-of-the-art information regarding effective rehabilitation measures for persons who have suffered a traumatic brain injury (TBI) and presents the conclusions and recommendations of the consensus panel regarding these issues.
Textbook of Hyperbaric Medicine
Part 1 Basic aspects: history of hyperbaric medicine physical, physiological and biochemical aspects of hyperbaric oxygenation effect of diving and high pressure environments on the human body
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