Hyperbaric oxygen therapy for reduction of secondary brain damage in head injury: an animal model of brain contusion.

  title={Hyperbaric oxygen therapy for reduction of secondary brain damage in head injury: an animal model of brain contusion.},
  author={Eilam Palzur and Eugene Vlodavsky and Hani Mulla and Ran Arieli and Moshe Feinsod and Jean Soustiel},
  journal={Journal of neurotrauma},
  volume={21 1},
Cerebral contusions are one the most frequent traumatic lesions and the most common indication for secondary surgical decompression. The purpose of this study was to investigate the physiology of perilesional secondary brain damage and evaluate the value of hyperbaric oxygen therapy (HBOT) in the treatment of these lesions. Five groups of five Sprague-Dawley rats each were submitted to dynamic cortical deformation (DCD) induced by negative pressure applied to the cortex. Cerebral lesions… 

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