Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial

@article{Collet2001HyperbaricOF,
  title={Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial},
  author={Jean-Paul Collet and Michel Vanasse and Pierre Marois and Maxime Amar and Joanne Goldberg and Jean Lambert and Maryse Lassonde and Paule Hardy and Jos{\'e}e Fortin and Ste´phane D Tremblay and D Montgomery and Jacques R Lacroix and Ann Robinson and Annette Majnemer},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={582-586}
}

Tables from this paper

Side effects of hyperbaric oxygen therapy in children with cerebral palsy.
TLDR
Side effects observed in a double-blind placebo-controlled multi-center randomized clinical trial carried out to assess the efficacy and safety of hyperbaric oxygen (HBO2) therapy in children with cerebral palsy were reported.
[Hyperbaric oxygen treatment for children with cerebral palsy].
TLDR
There are no scientific evidences for the use of HO in children with CP, and the Southern Africa Undersea and Hyperbaric Association discouraged the ongoing, widespread, and informal use of the therapy in South Africa based on the results of this randomized controlled study.
Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy.
TLDR
A double-blind placebo study to investigate the claim that hyperbaric oxygen treatment (HBO2) improves the cognitive status of children with cerebral palsy, finding no statistical difference between the two treatments.
Systematic review of hyperbaric oxygen therapy for cerebral palsy: the state of the evidence
TLDR
Both HBOT and pressurized room air resulted in improvements in motor function compared with baseline, and similar improvements were seen in the observational studies.
Hyperbaric oxygen treatment
TLDR
It is a blatant misrepresentation to refer to Collet et al’s study to claim that HBOT is not effective, according to a senior clinician involved in the largest randomized trial of hyperbaric oxygen treatment (HBOT) for children with cerebral palsy (CP).
Hyperbaric oxygen therapy in cerebral palsy
TLDR
Three randomized controlled trials provide moderate strength of evidence that HBO does not improve gross motor function compared with slightly pressurized room air or wait-list controls, but these findings are controversial due to the nature of the control used and the limited number of patients studied.
Hyperbaric Oxygen Therapy in the treatment of cerebral palsy : a review and comparison to currently accepted theories
  • Medicine
  • 2007
TLDR
Hyperbaric oxygenation therapy (HBOT) in the treatment of certain conditions (for example: decompression accidents, gas gangrene, burns) is supported by substantial clinical literature, and its use in some conditions has proved ineffective, and in others, especially neurologic, it has been very controversial.
‘Hyperbaric oxygen therapy and cerebral palsy’
TLDR
The children in both groups improved an average of ten times more during the two months of HBO treatment (whilst all other therapies and medication were stopped) than during the three months follow-up (when medication and all the ancillary treatments were restarted).
Hyperbaric Oxygenation Therapy in the Treatment of Cerebral Palsy : A Review and Comparison to Currently Accepted Therapies
TLDR
Hyperbaric oxygenation therapy (HBOT) in the treatment of certain conditions (for example: decompression accidents, gas gangrene, burns) is supported by substantial clinical literature, and its use in some conditions has proved ineffective, and in others, especially neurologic, it has been very controversial.
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