Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of osteosarcoma.

  title={Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of osteosarcoma.},
  author={Yasuomi Kawasoe and Masahiro Yokouchi and Yoshinori Ueno and Hiroaki Iwaya and Hiroki Yoshida and Setsuro Komiya},
  journal={Oncology reports},
  volume={22 5},
Although hyperbaric oxygen has been shown to enhance the efficacy of radiotherapy and chemotherapy for the treatment of several malignant tumors, the impact of hyperbaric oxygen on osteosarcoma has not yet been demonstrated. In this study, we investigated the efficacy of hyperbaric oxygen alone and in combination with an anti-cancer drug as an adjuvant to chemotherapy. In vitro, highly metastatic murine osteosarcoma cell lines were exposed to hyperbaric oxygen and cell viability was examined… CONTINUE READING


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