Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial: Unfortunate methodological flaws

@article{Gorman1999HyperbaricON,
  title={Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial: Unfortunate methodological flaws},
  author={Des Gorman},
  journal={Medical Journal of Australia},
  year={1999},
  volume={170}
}
  • D. Gorman
  • Published 1 June 1999
  • Medicine
  • Medical Journal of Australia
In the 1 March 1999 issue of the Journal, we published a research article that challenged the conventional wisdom on treatment for carbon monoxide poisoning. Here, the authors of that study answer criticisms and commendations of their work. 
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    Citation Type

    The use of hyperbaric oxygen therapy for carbon monoxide poisoning in Europe.
    TLDR
    While transient or prolonged unconsciousness was unanimously recognized as an indication for HBO₂ therapy, positive neurological findings, ECG suggesting acute ischemia and pregnancy were considered important indications of HBO⁂ therapy in more than 95% of the centers.
    Carbon monoxide poisoning.
    TLDR
    HBOT may be considered in patients who have persistent symptoms despite NBO, metabolic acidosis, abnormalities on neuropsychometric testing, or significantly elevated levels, and the ideal regimen of oxygen therapy has yet to be determined, and significant controversy exists regarding HBOT protocols.
    Carbon monoxide poisoning.
    TLDR
    HBOT may be considered in patients who have persistent symptoms despite NBO, metabolic acidosis, abnormalities on neuropsychometric testing, or significantly elevated levels, and HBOT accelerates dissociation of CO from hemoglobin and may also prevent DNS.
    COMPUTATIONAL ANALYSES OF THE UPTAKE AND DISTRIBUTION OF CARBON MONOXIDE (CO) IN HUMAN SUBJECTS
    OF DISSERTATION
    Predicting sporting outcomes: a statistical approach
    TLDR
    This document summarizes current capabilities, research and operational priorities, and plans for further studies that were established at the 2015 USGS workshop on quantitative hazard assessments of earthquake-triggered landsliding and liquefaction in the Czech Republic.
    Comments on "Hyperbaric Oxygen Therapy Did Not Prevent Delayed Neuropsychiatric Sequelae in a Prospective Observational Study With Propensity Score Matching in 224 Patients With Acute Carbon Monoxide Toxicity".
    The dilemma of managing carbon monoxide poisoning.
    • G. Emerson
    • Medicine
      Emergency medicine Australasia : EMA
    • 2004

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