Hyperbaric Oxygen Enhances the Expression of Prion Protein and Heat Shock Protein 70 in a Mouse Neuroblastoma Cell Line

@article{Shyu2004HyperbaricOE,
  title={Hyperbaric Oxygen Enhances the Expression of Prion Protein and Heat Shock Protein 70 in a Mouse Neuroblastoma Cell Line},
  author={Woei-cherng Shyu and S Lin and Keiichi Saeki and Astsutaka Kubosaki and Yoshitsugu Matsumoto and Takashi Onodera and M F Chiang and Peterus Thajeb and Hung Li},
  journal={Cellular and Molecular Neurobiology},
  year={2004},
  volume={24},
  pages={257-268}
}
1. Cellular prion protein, PrPC, is a ubiquitous glycoprotein strongly expressed in neurons with an as yet unknown biological function. In previous studies, we demonstrated that PrPC could be regulated by heat shock stress, implying that it might be a stress-responsive protein. Hyperbaric oxygen (HBO) administration is a well-defined model for the study of oxidative stress. 2. This study investigated the effect of HBO on PrPC and Hsp 70 expression in mouse neuroblastoma cell lines (N18… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Inhibition of the ubiquitin-proteasome pathway

  • P. M. Kloetzel, V. Stangel
  • 2002

Inhibition of the ubiquitinproteasome pathway induces differential heat shock protein response in cardiomyocytes and renders early cardiac protection

  • K. Stangel, C. Gunther, +8 authors V. Stangel
  • Biochem . Biophys . Res . Commun .
  • 2002
1 Excerpt

Similar Papers

Loading similar papers…