Hyperalgesia and laser evoked potentials alterations in hemiparkinson: evidence for an abnormal nociceptive processing.

@article{Tinazzi2009HyperalgesiaAL,
  title={Hyperalgesia and laser evoked potentials alterations in hemiparkinson: evidence for an abnormal nociceptive processing.},
  author={Michele Tinazzi and Serena Recchia and Sara Simonetto and Giovanni Defazio and Stefano Tamburin and Giuseppe Moretto and Antonio Fiaschi and Roberto Miliucci and Massimiliano Valeriani},
  journal={Journal of the neurological sciences},
  year={2009},
  volume={276 1-2},
  pages={153-8}
}
A number of patients with Parkinson's Disease (PD) complain of painful sensations that might be related not only to peripheral factors (muscle spasms, postural abnormalities) but also to an abnormal processing of nociceptive inputs in the Central Nervous System (CNS). To test this hypothesis, we recorded scalp CO(2) laser evoked potentials (LEPs) to foot skin stimulation in 11 pain-free treated PD patients affected by hemiparkinson (during the off state), in 6 pain-free drug-naïve… CONTINUE READING

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