Hyperalbuminemia and elevated transaminases associated with high-protein diet

  title={Hyperalbuminemia and elevated transaminases associated with high-protein diet},
  author={Ece A. Mutlu and Ali Keshavarzian and G{\"o}khan M. Mutlu},
  journal={Scandinavian Journal of Gastroenterology},
  pages={759 - 760}
While high protein diets are increasing in popularity, there is a lack of data on their potential adverse effects. We describe two patients on high protein supplements and exercising for physical fitness. Both developed intermittent abdominal pain, transient elevations in transaminases and hyperalbuminemia without there being any identifiable cause. The symptoms and abnormalities on the laboratory tests resolved after the high protein intake was discontinued. While the pathogenesis and… 
Adverse Effects of High Protein Diet {Above the Recommended Dietary Allowance} and Concept of Diet According to Ayurveda
It is suggested that there is currently no reasonable scientific basis in the literature to recommend protein consumption above the current RDA (high protein diet) for healthy adults due to its potential disease risks.
Adverse Effect in Human Beings Associated with Excess Dietary Protein Intake
The present article focused on the basic evidence about the protein-rich diets, excess protein intake, and various disorders fashioned in the human body by excessprotein intake.
Hyperalbuminemia associated with hepatocellular carcinoma in a dog.
It is hypothesized that hyperalbuminemia developed secondary to hepatocellular carcinoma due to increased synthesis of albumin by malignant hepatocytes or due to decreased negative feedback from impaired hepato cellular osmoreceptivity.
Adverse Effects Associated with Protein Intake above the Recommended Dietary Allowance for Adults
  • Ioannis Delimaris
  • Medicine
    ISRN nutrition
  • 2013
The findings of the present study suggest that there is currently no reasonable scientific basis in the literature to recommend protein consumption above the current RDA (high protein diet) for healthy adults due to its potential disease risks.
The Therapeutic use of human albumin in cancer patients' management.
Abstract : Vegetarian lacto-ovo is one of three large groups of vegetarians, where this type eating vegetable foodstuffs and abstained all kinds of meat, but still consumes milk and eggs. Vegetarian
Whey Protein Concentrate WPC-80 Intensifies Glycoconjugate Catabolism and Induces Oxidative Stress in the Liver of Rats
WPC-80 is responsible for intensive remodelling of liver tissue and induction of oxidative stress especially at a dose of 0.5 g/kg body weight, and enhanced level of GSH, MDA, IL-1β and TGF-β1 were also observed.
Effects of dietary lysine levels on the concentrations of selected nutrient metabolites in blood plasma of late‐stage finishing pigs
Thorough understanding how the plasma metabolite profile is alternated by dietary lysine will facilitate nutrient management for more sustainable swine production and indicated that the plasma metabolites profile can be affected by changing dietaryLysine content only.
Blood Serum Metabolite and Volatile Fatty Acid Profiles of Finishing Pigs Fed Diets with High and Low Levels of Energy and Crude Protein
Dietary imbalances in energy and protein affect BSM and VFA profile may be good indicators to detect unbalanced diets in pig farms, especially serum urea nitrogen, to detect an excess of protein.


Effects of high protein, high carbohydrate, and high fat diets on laboratory parameters.
Six normal volunteers consumed high protein, high carbohydrate, and high fat isocaloric diets on a metabolic ward for 10 days each; serum creatinine, BUN, albumin, and total protein exceeded the normal range in one to four subjects.
Effect of dietary protein intake on albumin homeostasis in nephrotic patients.
Dietary protein restriction in patients with established nephrosis results in decreased urinary albumin excretion in excess of any reduction in creatinine clearance, and total albumin mass is preserved and plasma albuminmass is actually increased during the period of dietary protein restriction.
The stimulation of albumin sythesis by methadone.
Investigation in rabbits maintained on daily methadone 4 mg per kg of body weight after a period of 3 months on increasing dosage found this hyperalbuminemic hypercatabolic state is not produceable in any other clinical or experimental situation.
Effects of an elemental diet in healthy volunteers.
Induction of cytosolic aspartate aminotransferase by glucagon in primary cultured rat hepatocytes.
Abbreviations: BMI0/body mass index
BUN0/blood urea nitrogen
Creatinine (mg/dl
HCO 3 (mEq/l, N: 24 Á30) 26 26 BUN (mg/dl