Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders.

@article{Keck2001HyperactivityOC,
  title={Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders.},
  author={Martin E. Keck and Florian Holsboer},
  journal={Peptides},
  year={2001},
  volume={22 5},
  pages={835-44}
}
Increasing evidence suggests that the neuroendocrine changes seen in psychiatric patients, especially in those suffering from affective disorders, may be causally related to the psychopathology and course of these clinical conditions. The most robustly confirmed neuroendocrine finding among psychiatric patients with affective disorders is hyperactivity of… CONTINUE READING