Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes.

@article{McPartlin2009HyperactivationOS,
  title={Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes.},
  author={Lori A McPartlin and Susan S. Suarez and Catherine A Czaya and Katrin Hinrichs and Sylvia J Bedford-Guaus},
  journal={Biology of reproduction},
  year={2009},
  volume={81 1},
  pages={199-206}
}
Capacitation is a complex and not well-understood process that encompasses all the molecular changes sperm must undergo to successfully fertilize an oocyte. In vitro fertilization has remained elusive in the horse, as evidenced by low in vitro fertilization (IVF) rates (0%-33%); moreover, only two foals have ever been produced using IVF. Incubation of stallion sperm in modified Whittens supplemented with bovine serum albumin and sodium bicarbonate yielded significant rates of time-dependent… CONTINUE READING
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