Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip

@article{Lamberty2004HydroxyzinePI,
  title={Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip},
  author={Y. Lamberty and A. Gower},
  journal={Pharmacology Biochemistry and Behavior},
  year={2004},
  volume={79},
  pages={119-124}
}
The present pharmacological study was conducted to investigate a possible role of the brain histaminergic system in vocalization induced in guinea pig pups by maternal separation and isolation in an unfamiliar environment. The effects of drugs acting at histamine receptors were determined after intraperitoneal injection, comprising hydroxyzine and chlorpheniramine, both histamine H1 antagonists, and the H3 agonist, immepip. A range of psychoactive drugs known to be active in this paradigm was… Expand
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