Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip
@article{Lamberty2004HydroxyzinePI, title={Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip}, author={Y. Lamberty and A. Gower}, journal={Pharmacology Biochemistry and Behavior}, year={2004}, volume={79}, pages={119-124} }
The present pharmacological study was conducted to investigate a possible role of the brain histaminergic system in vocalization induced in guinea pig pups by maternal separation and isolation in an unfamiliar environment. The effects of drugs acting at histamine receptors were determined after intraperitoneal injection, comprising hydroxyzine and chlorpheniramine, both histamine H1 antagonists, and the H3 agonist, immepip. A range of psychoactive drugs known to be active in this paradigm was… Expand
4 Citations
Pharmacological and methodological aspects of the separation-induced vocalization test in guinea pig pups; a systematic review and meta-analysis.
- Psychology, Medicine
- European journal of pharmacology
- 2015
- 8
- PDF
Neuroendocrine Regulation of Anxiety: Beyond the Hypothalamic‐Pituitary‐Adrenal Axis
- Medicine
- Journal of neuroendocrinology
- 2016
- 11
References
SHOWING 1-10 OF 49 REFERENCES
Reduction of guinea pig pup isolation calls by anxiolytic and antidepressant drugs
- Psychology, Medicine
- Psychopharmacology
- 1996
- 54
- Highly Influential
Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice
- Chemistry, Medicine
- Neuropharmacology
- 2000
- 165
- Highly Influential
H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat.
- Chemistry, Medicine
- Pharmacological research
- 2003
- 30
Effects of histamine H3 receptor ligands in experimental models of anxiety and depression
- Medicine, Psychology
- Psychopharmacology
- 1999
- 57
Distress vocalization in rat pups. A simple screening method for anxiolytic drugs.
- Medicine
- Journal of pharmacological methods
- 1985
- 174
Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function.
- Medicine, Chemistry
- The Journal of pharmacology and experimental therapeutics
- 2001
- 87
- Highly Influential
- PDF
In vivo modulation of rat hypothalamic histamine release by the histamine H3 receptor ligands, immepip and clobenpropit. Effects of intrahypothalamic and peripheral application.
- Chemistry, Medicine
- European journal of pharmacology
- 1998
- 51
- Highly Influential
Effects of a novel potential antidepressant on the behavior and cortisol levels of isolated guinea pig pups
- Biology, Medicine
- Pharmacology Biochemistry and Behavior
- 2001
- 7
Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics
- Psychology, Medicine
- Psychopharmacology
- 2005
- 137
- Highly Influential