Hydroxyurea-induced leg ulcers treated with a protease-modulating matrix.

BACKGROUND The development of painful leg ulcers in the ankle area is a rare and only partially described complication in patients receiving high-dose, long-term hydroxyurea treatment for myeloproliferative diseases. Several reports have described treatments for chronic wound management with this type of lesion. OBSERVATIONS We describe 2 patients who… CONTINUE READING