Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation.

  title={Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation.},
  author={Lijuan Sun and Cheng Si Luo and Jiankang Liu},
  journal={Food & function},
  volume={5 8},
Cancer cells are usually under higher levels of oxidative stress compared to normal cells. We hypothesized that the introduction of additional reactive oxygen species (ROS) or the suppression of antioxidant activity may selectively enhance cancer cell killing by generating oxidative agents through stress overload or stress sensitization. The aim of this work was to test whether hydroxytyrosol (HT), one of the major polyphenolic constituents of extra virgin olive oil, could exert anti-cancer… CONTINUE READING
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