Hydroxytyrosol Ameliorates Endothelial Function under Inflammatory Conditions by Preventing Mitochondrial Dysfunction

@inproceedings{Calabriso2018HydroxytyrosolAE,
  title={Hydroxytyrosol Ameliorates Endothelial Function under Inflammatory Conditions by Preventing Mitochondrial Dysfunction},
  author={Nadia Calabriso and Antonio Gnoni and Eleonora Stanca and Alessandro Cavallo and Fabrizio Damiano and Luisa Siculella and Maria Annunziata Carluccio},
  booktitle={Oxidative medicine and cellular longevity},
  year={2018}
}
Mitochondria are fundamental organelles producing energy and reactive oxygen species (ROS); their impaired functions play a key role in endothelial dysfunction. Hydroxytyrosol (HT), a well-known olive oil antioxidant, exerts health benefits against vascular diseases by improving endothelial function. However, the HT role in mitochondrial oxidative stress in endothelial dysfunction is not clear yet. To investigate the HT effects on mitochondrial ROS production in the inflamed endothelium, we… CONTINUE READING

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