Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice.

  title={Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice.},
  author={Ming Jin and Yan Wu and Lin Wang and Baoxia Zang and Li Song Tan},
  journal={Phytotherapy research : PTR},
  volume={30 4},
Hydroxysafflor yellow A (HSYA) is an active component of Carthamus tinctorius L., and we want to investigate whether HSYA attenuates pulmonary fibrosis induced by bleomycin (BLM) in mice. The mice received a BLM via oropharyngeal aspiration, and HSYA was intraperitoneally injected. Arterial blood gas analysis was performed. Morphological changes and hydroxyproline content were measured. mRNA expression of transforming growth factor-β1 (TGF-β1), connective tissue growth factor, α-smooth muscle… CONTINUE READING


Publications citing this paper.
Showing 1-7 of 7 extracted citations

Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases

Evidence-based complementary and alternative medicine : eCAM • 2018
View 12 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…