Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines.

@article{Ravindra2016HydroxyphenylationOH,
  title={Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines.},
  author={Kodihalli C. Ravindra and Laura J. Trudel and John S. Wishnok and Gerald N. Wogan and Steven R Tannenbaum and Paul L. Skipper},
  journal={ACS chemical biology},
  year={2016},
  volume={11 5},
  pages={1230-7}
}
Monocyclic aromatic amines are widespread environmental contaminants with multiple sources such as combustion products, pharmaceuticals, and pesticides. Their phenolic metabolites are converted intracellularly to electrophilic quinone imines upon autoxidation and can embed in the cellular matrix through a transimination reaction that leaves a redox-active… CONTINUE READING