Hydroxyl radical generation by coal mine dust: possible implication to coal workers' pneumoconiosis (CWP).

@article{Dalal1995HydroxylRG,
  title={Hydroxyl radical generation by coal mine dust: possible implication to coal workers' pneumoconiosis (CWP).},
  author={Nar S. Dalal and Julie Newman and Donna L Pack and Scott F Leonard and Val Vallyathan},
  journal={Free radical biology & medicine},
  year={1995},
  volume={18 1},
  pages={11-20}
}
Occupational exposure to coal mine dust causes coal workers' pneumoconiosis (CWP) and other pulmonary diseases by mechanisms that remain unclear. Because the hydroxyl radicals (.OH) may play an important role in the pathogenesis of CWP, we studied the potential role of bituminous coal mine dust samples for catalyzing the generation of .OH from hydrogen peroxide (H2O2). These coal mine dusts evaluated represented two geographic areas with diversity in CWP prevalence. Electron spin resonance (ESR… CONTINUE READING