Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.

Abstract

Leukotriene B(4), an arachidonate metabolite, is a potent chemoattractant of leukocytes involved in various inflammatory diseases. Two G-protein-coupled receptors for leukotriene B(4) have been cloned and characterized. BLT1 (Yokomizo, T., Izumi, T., Chang, K., Takuwa, Y., and Shimizu, T. (1997) Nature 387, 620-624) is a high affinity receptor exclusively… (More)

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@article{Yokomizo2001HydroxyeicosanoidsBT, title={Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.}, author={Takehiko Yokomizo and K. Kato and Hiroshi Hagiya and T. Izumi and T. Shimizu}, journal={The Journal of biological chemistry}, year={2001}, volume={276 15}, pages={12454-9} }