• DOI:10.1586/era.11.10
Corpus ID: 22568536

Hydroxycarbamide: a user’s guide for chronic myeloproliferative disorders

@article{Spivak2011HydroxycarbamideAU,
  title={Hydroxycarbamide: a user’s guide for chronic myeloproliferative disorders},
  author={J. Spivak and H. Hasselbalch},
  journal={Expert Review of Anticancer Therapy},
  year={2011},
  volume={11},
  pages={403 - 414}
}

• J. Spivak, H. Hasselbalch
• Published 2011
• Medicine
• Expert Review of Anticancer Therapy

Hydroxycarbamide is a nonalkylating antiproliferative and antiviral agent that has been used for over 40 years to treat a variety of neoplastic and non-neoplastic conditions. Hydroxycarbamide is readily absorbed and widely distributed throughout the body. It acts primarily to inhibit DNA synthesis, which underpins its use in solid tumors, viral infections and chronic myeloproliferative disorders. Hydroxycarbamide is an effective treatment for preventing transient ischemic attacks associated… Expand

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