Hydroxyamide analogues of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity

Abstract

Departments of Anesthesiology (M.K.P., N.J.H.), Neurology (J.K.), Chemistry (P.J.J., H.S.E., Y.W., M.L.B.) and Neuroscience Graduate Program (N.J.H.), University of Virginia, Charlottesville, Virginia Anticonvulsant Drug Development (ADD) Program, Department of Pharmacology and Toxicology, (M.D.S., H.S.W.), University of Utah, Salt Lake City, Utah JPET Fast… (More)

Topics

2 Figures and Tables

Cite this paper

@inproceedings{Jones2006HydroxyamideAO, title={Hydroxyamide analogues of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity}, author={Paulianda J. Jones and Yuesheng Wang and Misty D. Smith and Nicholas James Hargus and Hilary Schenck Eidam and Henry S White and Jaideep Kapur and Milton L. Brown and Manoj K Patel}, year={2006} }