Hydrothermal Reactions of Pyruvic Acid: Synthesis, Selection, and Self-Assembly of Amphiphilic Molecules

@article{Hazen2006HydrothermalRO,
  title={Hydrothermal Reactions of Pyruvic Acid: Synthesis, Selection, and Self-Assembly of Amphiphilic Molecules},
  author={R. Hazen and D. Deamer},
  journal={Origins of Life and Evolution of Biospheres},
  year={2006},
  volume={37},
  pages={143-152}
}
  • R. Hazen, D. Deamer
  • Published 2006
  • Chemistry, Medicine
  • Origins of Life and Evolution of Biospheres
Selection and self-assembly of organic compounds in aqueous phases must have been a primary process leading to emergent molecular complexity and ultimately to the origin of life. Facile reactions of pyruvic acid under hydrothermal conditions produce a complex mixture of larger organic molecules, some of which are amphiphiles that readily self-assemble into cell-sized vesicular structures. Chemical characterization of major components of this mixture reveals similarities to the suite of organic… Expand
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