Hydrostatic pressure regulates tight junctions, actin cytoskeleton and transcellular ion transport.

@article{Tokuda2009HydrostaticPR,
  title={Hydrostatic pressure regulates tight junctions, actin cytoskeleton and transcellular ion transport.},
  author={Shinsaku Tokuda and H. Miyazaki and K. Nakajima and Toshiki Yamada and Y. Marunaka},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={390 4},
  pages={
          1315-21
        }
}
In the epithelia and endothelia, tight junctions regulate the movement of several substances through the paracellular pathway, maintaining several gradients between apical and basal compartments including osmolality and hydrostatic pressure. In this study, we show that the change of hydrostatic pressure gradient affected tight junctions as well as actin cytoskeleton, cell height and transcellular ion transport. Hydrostatic pressure gradient from basolateral to apical side increased… Expand
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