Hydrostatic pressure promotes the acidification of vacuoles in Saccharomyces cerevisiae.

@article{Abe1995HydrostaticPP,
  title={Hydrostatic pressure promotes the acidification of vacuoles in Saccharomyces cerevisiae.},
  author={Fumiyoshi Abe and Koki Horikoshi},
  journal={FEMS microbiology letters},
  year={1995},
  volume={130 2-3},
  pages={
          307-12
        }
}
Application of hydrostatic pressure caused a delay or cessation of cell growth in Saccharomyces cerevisiae. The yeast vacuole is an acidic organelle involved in cellular ion homeostasis and degradation of proteins. Hydrostatic pressure promoted the acidification of the vacuoles in the strain IFO 2347. A pressure of 40 to 60 MPa reduced the vacuolar pH, defined using 6-carboxyfluorescein, from 6.05 to 5.88, while a pressure of 20 MPa did not affect the pH. Similar results were obtained with the… CONTINUE READING

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