Hydrophobicity engineering to facilitate surface display of heterologous gene products on Staphylococcus xylosus.

Abstract

Protein engineering has been employed to investigate the effect of specific amino acid changes on the targeting of heterologous proteins to the outer cell surface of the Gram-positive bacterium Staphylococcus xylosus. Three different variants, corresponding to a 101 amino acid region of the major glycoprotein (G protein) of human respiratory syncytial virus… (More)

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