Hydrophobic grafting enhances low molecular polyethylenimine ’ s delivery of plasmid DNA into mammalian cells

@inproceedings{Liu2013HydrophobicGE,
  title={Hydrophobic grafting enhances low molecular polyethylenimine ’ s delivery of plasmid DNA into mammalian cells},
  author={Shan Liu and Fei-fei Yang and Qi-Ming Wang and Wei Huang and Ming-ji Jin and Zhong-gao Gao},
  year={2013}
}
SUMMARY The gene transfer efficiency of a low molecular weight of polyethyleneimine was elevated by hydrophobic grafting. Physicochemical and biological studies showed that hydrophobic grafting offered PEI/pDNA polyplexes greater stability and improved affinity to mammalian cell membranes, and so enhanced the cellular delivery and the ultimate gene transfer… CONTINUE READING