Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice.

Abstract

The clinical management of human brucellosis is still challenging and demands in vitro active antibiotics capable of targeting the pathogen-harboring intracellular compartments. A sustained release of the antibiotic at the site of infection would make it possible to reduce the number of required doses and thus the treatment-associated toxicity. In this… (More)
DOI: 10.1128/AAC.00378-13

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Cite this paper

@article{Imbuluzqueta2013HydrophobicGN, title={Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice.}, author={Edurne Imbuluzqueta and Carlos Gamazo and Hugo Lana and Miguel {\'A}ngel Campanero and David Salas and Ana Gloria Gil and Elisa Elizondo and Nora Ventosa and Jaume Veciana and Mar{\'i}a Jos{\'e} Blanco-Pr{\'i}eto}, journal={Antimicrobial agents and chemotherapy}, year={2013}, volume={57 7}, pages={3326-33} }