Hydrophobic adsorption and covalent immobilization of Candida antarctica lipase B on mixed-function-grafted silica gel supports for continuous-flow biotransformations

@inproceedings{Borosa2013HydrophobicAA,
  title={Hydrophobic adsorption and covalent immobilization of Candida antarctica lipase B on mixed-function-grafted silica gel supports for continuous-flow biotransformations},
  author={Zolt{\'a}n Borosa and Di{\'a}na Weisera and M{\'a}ria M{\'a}rkusa and Emese Abah{\'a}ziov{\'a}a and {\'A}gnes Magyara and Anna Tomina and B{\'e}la Koczkac and P{\'e}ter Kov{\'a}csd and L{\'a}szl{\'o} Poppea},
  year={2013}
}
  • Zoltán Borosa, Diána Weisera, +6 authors László Poppea
  • Published 2013
Adsorption onto solid supports has proven to be an easy and effective way to improve the mechanical and catalytic properties of lipases. Covalent binding of lipases onto the support surface enhances the active lifetime of the immobilized biocatalysts. Our study indicates that mesoporous silica gels grafted with various functions are ideal supports for both adsorptive and covalent binding for lipase B from Candida antarctica (CaLB). Adsorption of CaLB on phenyl-functionalized silica gels… CONTINUE READING

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