Hydromorphone: pharmacology and clinical applications in cancer patients

@article{Sarhill2001HydromorphonePA,
  title={Hydromorphone: pharmacology and clinical applications in cancer patients},
  author={Nabeel Sarhill and Declan Walsh and Kristine A. Nelson},
  journal={Supportive Care in Cancer},
  year={2001},
  volume={9},
  pages={84-96}
}
Abstract Hydromorphone is a more potent opioid analgesic than morphine and is used for moderate to severe pain. It can be administered by injection, by infusion, by mouth, and rectally. Oral bioavailability is low. The kidney excretes hydromorphone and its metabolites. Some metabolites may have greater analgesic activity than hydromorphone itself but are unlikely to contribute to the pharmacological activity of hydromorphone. With the exception of pruritus, sedation and nausea and vomiting… 

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