Hydrolysis of several glycol ether acetates and acrylate esters by nasal mucosal carboxylesterase in vitro.

@article{Stott1985HydrolysisOS,
  title={Hydrolysis of several glycol ether acetates and acrylate esters by nasal mucosal carboxylesterase in vitro.},
  author={William T Stott and Michael J McKenna},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1985},
  volume={5 2},
  pages={399-404}
}
The in vitro activity of carboxylesterase recovered from the nasal mucosal tissue of B6C3F1/CrlBR mice toward several agents known to cause olfactory epithelial lesions when inhaled by rodents was determined. Apparent Vmax and Km values were obtained for mouse nasal carboxylesterase using ethylene glycol monomethyl ether acetate (EGMEAc), ethylene glycol monoethyl ether acetate (EGEEAc), propylene glycol monomethyl ether acetate (PGMEAc), methyl acrylate (ME), ethyl acrylate (EA), and butyl… CONTINUE READING
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