Hydrolysis of erythrocyte proteins by proteases of malaria parasites.

@article{Rosenthal2002HydrolysisOE,
  title={Hydrolysis of erythrocyte proteins by proteases of malaria parasites.},
  author={Philip J. Rosenthal},
  journal={Current opinion in hematology},
  year={2002},
  volume={9 2},
  pages={
          140-5
        }
}
During the intraerythrocytic phase of the life cycle, malaria parasites hydrolyze host proteins. Hemoglobin is processed into individual amino acids, which are used for parasite protein synthesis. Erythrocyte cytoskeletal proteins are cleaved during erythrocyte invasion and rupture. A number of plasmodial proteases that appear to be responsible for key cleavages of host proteins have recently been characterized. Hemoglobin hydrolysis appears to be mediated by acid cysteine, aspartic, and… CONTINUE READING

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