Corpus ID: 6254542

Hydrolysis of N- and S-monomethyl derivatives of 2-thiophenobarbital.

@article{Tarsa2003HydrolysisON,
  title={Hydrolysis of N- and S-monomethyl derivatives of 2-thiophenobarbital.},
  author={Monika Tarsa and G. Żuchowski and J. Bojarşki},
  journal={Acta poloniae pharmaceutica},
  year={2003},
  volume={60 4},
  pages={
          247-52
        }
}
Kinetics of hydrolysis of S-methyl-2-thiophenobarbital in aqueous solutions was investigated using the UV spectroscopic method within the pH range 1.5-12.9 at 60 degrees C. Chromatography was used to separate and isolate the products of hydrolysis of this compound and its N-methyl isomer. The products were identified by spectroscopic methods and the course of hydrolysis of both isomers were compared. 
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