Hydrogen sulfide raises cytosolic calcium in neurons through activation of L-type Ca2+ channels.

@article{GarcaBereguian2008HydrogenSR,
  title={Hydrogen sulfide raises cytosolic calcium in neurons through activation of L-type Ca2+ channels.},
  author={Miguel Angel Garc{\'i}a-Bereguia{\'i}n and Alejandro Khalil Samhan-Arias and Francisco Javier Martin-Romero and Carlos Gutierrez-Merino},
  journal={Antioxidants & redox signaling},
  year={2008},
  volume={10 1},
  pages={31-42}
}
Hydrogen sulfide (H(2)S) concentration can be maintained in cell cultures within the range reported for rat brain by repetitive pulses of sodium hydrogen sulfide. Less than 2 h exposure to H(2)S concentrations within 50 and 120 microM (i.e., within the upper segment of the reported physiological range of H(2)S in rat brain), produces a large shift of the intracellular calcium homeostasis in cerebellar granule neurons (CGN) in culture, leading to a large and sustained increase of cytosolic… CONTINUE READING