Hydrogen sulfide may improve the hippocampal damage induced by recurrent febrile seizures in rats.

@article{Han2005HydrogenSM,
  title={Hydrogen sulfide may improve the hippocampal damage induced by recurrent febrile seizures in rats.},
  author={Ying Han and Jiong Qin and Xingzhi Chang and Zhi-xian Yang and Xiuying Tang and Junbao Du},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={327 2},
  pages={431-6}
}
The aim of the present study was to investigate the possible role of hydrogen sulfide (H(2)S) in the pathogenesis of recurrent febrile seizures (FS) in rats. On a rat model of recurrent FS, the ultrastructure of hippocampal neurons, the plasma level of H(2)S, the expressions of cystathionine b-synthase (CBS) and c-fos, and the development of mossy fiber sprouting (MFS) in hippocampus were examined after treatment with NaHS, a donor of H(2)S, or hydroxylamine (HA), an inhibitor of CBS. We found… CONTINUE READING

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