Hydrogen sulfide attenuates surgical trauma-induced inflammatory response and cognitive deficits in mice.

@article{Chu2013HydrogenSA,
  title={Hydrogen sulfide attenuates surgical trauma-induced inflammatory response and cognitive deficits in mice.},
  author={Qin-jun Chu and Long He and Wei Zhang and Chun-lan Liu and Yan-Qiu Ai and Qi Zhang},
  journal={The Journal of surgical research},
  year={2013},
  volume={183 1},
  pages={330-6}
}
BACKGROUND It has been increasingly reported that peripheral surgical trauma triggers neuroinflammatory processes associated with postoperative cognitive dysfunction, and that mitigating the neuroinflammatory effects of surgery prevents surgery-induced cognitive dysfunction. Endogenously produced hydrogen sulfide (H2S) has multiple functions in the brain, and an increasing number of studies have demonstrated its anti-inflammatory effects. The present study was designed to investigate the… CONTINUE READING