Hydrogen sulfide as an endothelium-derived hyperpolarizing factor in rodent mesenteric arteries.

@article{Edwards2012HydrogenSA,
  title={Hydrogen sulfide as an endothelium-derived hyperpolarizing factor in rodent mesenteric arteries.},
  author={Gillian Edwards and Michel F{\'e}l{\'e}tou and Arthur H. Weston},
  journal={Circulation research},
  year={2012},
  volume={110 1},
  pages={e13-4; author reply e15-6}
}
Hydrogen Sulfide as an Endothelium-Derived Hyperpolarizing Factor in Rodent Mesenteric Arteries To the Editor: We read with interest the article by Mustafa et al1 in Circulation Research in which the authors suggest that hydrogen sulfide is a major endothelium-derived hyperpolarizing factor (EDHF) that generates endothelial and vascular myocyte hyperpolarization and relaxation by predominantly activating ATP-sensitive potassium channels (KATP) through cysteine S-sulfhydration. As previously… CONTINUE READING