Hydrogen sulfide as a potent cardiovascular protective agent.

  title={Hydrogen sulfide as a potent cardiovascular protective agent.},
  author={Xiao-hua Yu and Li-Bao Cui and Kai Wu and Xi-long Zheng and Francisco S Cayabyab and Zhi-Wei Chen and Chao-ke Tang},
  journal={Clinica chimica acta; international journal of clinical chemistry},
Hydrogen sulfide (H2S) is a well-known toxic gas with the characteristic smell of rotten eggs. It is synthesized endogenously in mammals from the sulfur-containing amino acid l-cysteine by the action of several distinct enzymes: cystathionine-γ-lyase (CSE), cystathionine-ß-synthase (CBS), and 3-mercaptopyruvate sulfurtransferase (3-MST) along with cysteine aminotransferase (CAT). In particular, CSE is considered to be the major H2S-producing enzyme in the cardiovascular system. As the third… CONTINUE READING
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