Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe

@inproceedings{Dufton2012HydrogenSA,
  title={Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe},
  author={Neil Dufton and Jane Mea Natividad and Elena F. Verd{\'u} and John L Wallace},
  booktitle={Scientific reports},
  year={2012}
}
Hydrogen sulfide is an essential gasotransmitter associated with numerous pathologies. We assert that hydrogen sulfide plays an important role in regulating macrophage function in response to subsequent inflammatory stimuli, promoting clearance of leukocyte infiltrate and reducing TNF-α levels in vivo following zymosan-challenge. We describe two distinct methods of measuring leukocyte hydrogen sulfide synthesis; methylene blue formation following zinc acetate capture and a novel fluorescent… CONTINUE READING