Hydrogen peroxide increases the activity of rat sympathetic preganglionic neurons in vivo and in vitro

@article{Lin2003HydrogenPI,
  title={Hydrogen peroxide increases the activity of rat sympathetic preganglionic neurons in vivo and in vitro},
  author={Hsun Hsun Lin and Cheng-Hsu Chen and W. -K Hsieh and T. H. Chiu and Chih-Chen Lai},
  journal={Neuroscience},
  year={2003},
  volume={121},
  pages={641-647}
}
Reactive oxygen species (ROS) have been shown to modulate neuronal synaptic transmission and have also been implicated in cardiovascular diseases such as hypertension. The hypothesis that H(2)O(2) acting on sympathetic preganglionic neurons (SPNs) affects spinal sympathetic outflow was tested in the present study. H(2)O(2) was applied intrathecally via an implanted cannula to the T7-T9 segments of urethane-anesthetized rats. Blood pressure and heart rate were used as indices to evaluate the… CONTINUE READING
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Biphasic effect

  • H Katsuki, C Nakanishi, H Saito, N Matsuki
  • 1997
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