Hydrogen peroxide-dependent DNA release and transfer of antibiotic resistance genes in Streptococcus gordonii.

@article{Itzek2011HydrogenPD,
  title={Hydrogen peroxide-dependent DNA release and transfer of antibiotic resistance genes in Streptococcus gordonii.},
  author={Andreas Itzek and Lanyan Zheng and Zhiyun Chen and Justin Merritt and Jens Kreth},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 24},
  pages={6912-22}
}
Certain oral streptococci produce H(2)O(2) under aerobic growth conditions to inhibit competing species like Streptococcus mutans. Additionally, H(2)O(2) production causes the release of extracellular DNA (eDNA). eDNA can participate in several important functions: biofilm formation and cell-cell aggregation are supported by eDNA, while eDNA can serve as a nutrient and as an antimicrobial agent by chelating essential cations. eDNA contains DNA fragments of a size that has the potential to… CONTINUE READING
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