Corpus ID: 5626800

Hydrogen magnetic reaction gene regulation

@article{Kim2012HydrogenMR,
  title={Hydrogen magnetic reaction gene regulation},
  author={Yeon Sook Kim and Dae Gwan Lee and Suk‐Keun Lee},
  journal={arXiv: Other Quantitative Biology},
  year={2012}
}
A new gene regulation system using weak magnetic field can induce the hydrogen magnetic reaction (HMR) in hydrogen atoms, and subsequently affect the electrostatic polarity of hydrogen bonds in DNA base pairs. The HMR can sequentially activate the DNA base pair polarities of target DNA. With the characteristic base pair polarities of DNA duplex the (pyrimidine)m-(purine)n DNA segment is a basic unit to maintain and to accumulate the electrostatic energy of DNA duplex (1). To enhance the… Expand

References

SHOWING 1-10 OF 30 REFERENCES
Positive and negative effects of DNA bending on activation of transcription from a distant site.
Transcription of the Escherichia coli glnHPQ operon, which encodes components of the high-affinity glutamine transport system, is activated by nitrogen regulator I (NRI)-phosphate in response toExpand
Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I
TLDR
By using torsionally constrained DNA molecules, the first single-molecule study of DNA translocation by the type I restriction enzyme EcoR124I is reported, finding that the enzyme tracks along the helical pitch of the DNA molecule. Expand
Role of specific cations and water entropy on the stability of branched DNA motif structures.
TLDR
Computer simulations in explicit water and salt on a model TWJ and free energy calculations are used to quantify the role of ionic character and strength on stability and find that enthalpic stabilization of the first and second hydration shells by Mg(2+) accounts for 1/3 and all of the free energy gain in 50% and pure MgCl(2) solutions, respectively. Expand
Correlation between DNA bending and transcriptional activation at a plasmid promoter.
TLDR
RNA polymerase is able to bend a DNA fragment containing PctII, suggesting that an increase in the RNA polymerase-DNA contacts is an important step in transcription initiation, and the upstream activating region could be substituted by targets of unrelated DNA-bending proteins, supporting the role of curved DNA as a transcriptional modulator. Expand
Differential charge polarization of axial histidines in bacterial reaction centers balances the asymmetry of the special pair.
TLDR
Solid-state NMR spectroscopy in conjunction with density functional theory modeling can resolve electronic structure down to the atomic level in large membrane proteins, and this work has used this technique to address the mechanisms underlying the photochemical reactivity of the special pair in the bacterial reaction center. Expand
Activation of Gene Expression by a Ligand-induced Conformational Change of a Protein-DNA Complex*
TLDR
Although binding of IlvY protein to the tandem operators is sufficient to repress ilvYpromoter-specific transcription, it is not sufficient to activate transcription from the ilvC promoter region, which results in a 100-fold increase in the affinity of RNA polymerase binding at theilVC promoter site. Expand
Evidence for sequence preferences in the intercalative binding of ethidium bromide to dinucleoside monophosphates.
TLDR
The combination of the optical spectroscopies and the nuclear magnetic resonance experiments on these model systems provides direct evidence for the intercalation model for the binding of ethidium bromide to double-stranded nucleic acids. Expand
Solution conformation and dynamics of the octadeoxy-nucleotide d(CACTAGTG)2: a multinuclear n.m.r. relaxation study.
  • A. Lane
  • Chemistry, Medicine
  • Carbohydrate research
  • 1991
TLDR
The conformation and internal dynamics of the octadeoxynucleotide d(CACTAGTG)2 have been examined by 1H- and 13C-n.m.O.r. relaxation methods and show that the terminal residues are relatively more mobile than the internal residues, and that the C-2'-H and C-3'-H vectors move with order parameters of 0.6-0.75. Expand
Transfer of parahydrogen-induced hyperpolarization to 19F.
TLDR
It is shown that PHIP-derived hyperpolarization is transferred to 19F not only in the Earth's magnetic field but also in a strong magnetic field when carrying out the reaction in the NMR spectrometer (PASADENA condition). Expand
Effect of salt on the hybridization of DNA by sequential immobilization of oligonucleotides at the air-water interface in the presence of ODA/DOTAP monolayers.
TLDR
Measurements clearly showed that the preformed duplexes retained their native form as double helices and further, hybridization of the complementary single-stranded DNA molecules had occurred at the air-water interface, leading to the characteristic double-helical structure. Expand
...
1
2
3
...