Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.

@article{Kohama2015HydrogenIP,
  title={Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.},
  author={Keisuke Kohama and Hayato Yamashita and Michiko Aoyama-Ishikawa and Toru Takahashi and Timothy R Billiar and Takeshi Nishimura and Joji Kotani and Atsunori Nakao},
  journal={Surgery},
  year={2015},
  volume={158 2},
  pages={399-407}
}
INTRODUCTION Hemorrhagic shock followed by fluid resuscitation (HS/R) triggers an inflammatory response and causes pulmonary inflammation that can lead to acute lung injury (ALI). Hydrogen, a therapeutic gas, has potent cytoprotective, antiinflammatory, and antioxidant effects. This study examined the effects of inhaled hydrogen on ALI caused by HS/R. METHODS Rats were subjected to hemorrhagic shock by withdrawing blood to lower blood pressure followed by resuscitation with shed blood and… CONTINUE READING
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