Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.

  title={Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.},
  author={M. Kajiya and Kimihiro Sato and M. Silva and K. Ouhara and P. M. Do and K. Shanmugam and T. Kawai},
  journal={Biochemical and biophysical research communications},
  volume={386 2},
  • M. Kajiya, Kimihiro Sato, +4 authors T. Kawai
  • Published 2009
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • It is well known that some intestinal bacteria, such as Escherichia coli, can produce a remarkable amount of molecular hydrogen (H(2)). Although the antioxidant effects of H(2) are well documented, the present study examined whether H(2) released from intestinally colonized bacteria could affect Concanavalin A (ConA)-induced mouse hepatitis. Systemic antibiotics significantly decreased the level of H(2) in both liver and intestines along with suppression of intestinal bacteria. As determined by… CONTINUE READING
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