Hydrogen and hydration of DNA and RNA oligonucleotides.

  title={Hydrogen and hydration of DNA and RNA oligonucleotides.},
  author={Muttaiya Sundaralingam and Baocheng Pan},
  journal={Biophysical chemistry},
  volume={95 3},
In this paper, hydrogen bonding interaction and hydration in crystal structures of both DNA and RNA oligonucleotides are discussed. Their roles in the formation and stabilization of oligonucleotides have been covered. Details of the Watson-Crick base pairs G.C and A.U in DNA and RNA are illustrated. The geometry of the wobble (mismatched) G.U base pairs and the cis and almost trans conformations of the mismatched U.U base pairs in RNA is described. The difference in hydration of the Watson… CONTINUE READING