Hydrogen Sulphide Production in Healthy and Ulcerated Gastric Mucosa of Rats

@inproceedings{BronowickaAdamska2017HydrogenSP,
  title={Hydrogen Sulphide Production in Healthy and Ulcerated Gastric Mucosa of Rats},
  author={Patrycja Bronowicka-Adamska and Maria Wr{\'o}bel and Marcin Magierowski and Katarzyna Magierowska and Sławomir Kwiecień and Tomasz Brzozowski},
  booktitle={Molecules},
  year={2017}
}
Hydrogen sulphide (H₂S) is produced endogenously via two enzymes dependent on pyridoxal phosphate (PLP): cystathionine beta-synthase (CBS, EC 4.2.1.22), cystathionase γ-liase (CTH, EC 4.4.1.1), and a third, 3-mercaptopyruvate sulfurtransferase (MPST, EC 2.8.1.2). H₂S strengthens the defence mechanisms of the gastric mucosal barrier, and plays an important role in gastroprotection, including the increased resistance to damage caused by various irritants and non-steroidal anti-inflammatory drugs… CONTINUE READING

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