Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species.

@article{Shi2016HydrogenRichSA,
  title={Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species.},
  author={Qiao Yue Shi and Chen Chen and Wen-hong Deng and Peng Wang and Teng Zuo and Liang Zhao and Jia Yu and Kai-liang Zhao and Fang-Chao Mei and Chen Li and Gui-rong Wang and Weixing Wang},
  journal={Pancreas},
  year={2016},
  volume={45 10},
  pages={
          1424-1431
        }
}
OBJECTIVES The objective of this study was to study the role of hydrogen-rich saline (HRS) on acute hepatic injury (AHI) in acute necrotizing pancreatitis (ANP). METHODS Rats were used for this study and an ANP model was induced by injecting 5% sodium taurocholate into the biliary-pancreatic duct. Experiments were performed in 3 groups: sham, ANP, and ANP + HRS (HRS). Animals were killed at 3, 12, and 24 hours after operation, and then blood and tissue samples were harvested. Various… CONTINUE READING
3
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Recent Advances in Studies of Molecular Hydrogen against Sepsis

  • International journal of biological sciences
  • 2019
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats

  • Medical science monitor : international medical journal of experimental and clinical research
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.

  • Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
  • 2017

Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.

  • Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
  • 2017