Hydrogels for lung tissue engineering: Biomechanical properties of thin collagen-elastin constructs.

@article{Dunphy2014HydrogelsFL,
  title={Hydrogels for lung tissue engineering: Biomechanical properties of thin collagen-elastin constructs.},
  author={Siobh{\'a}n E Dunphy and Jessica A J Bratt and Khondoker Mehedi Akram and Nicholas Robert Forsyth and Alicia J El Haj},
  journal={Journal of the mechanical behavior of biomedical materials},
  year={2014},
  volume={38},
  pages={251-9}
}
In this study, collagen-elastin constructs were prepared with the aim of producing a material capable of mimicking the mechanical properties of a single alveolar wall. Collagen has been used in a wide range of tissue engineering applications; however, due to its low mechanical properties its use is limited to non load-bearing applications without further manipulation using methods such as cross-linking or mechanical compression. Here, it was hypothesised that the addition of soluble elastin to… CONTINUE READING