Hydrodynamic trapping measures the interaction between membrane-associated molecules

@inproceedings{Junghans2018HydrodynamicTM,
  title={Hydrodynamic trapping measures the interaction between membrane-associated molecules},
  author={Victoria Junghans and Jana Hlad{\'i}lkov{\'a} and Ana M Santos and Mikael Lund and Simon J Davis and Peter J{\"o}nsson},
  booktitle={Scientific Reports},
  year={2018}
}
How membrane proteins distribute and behave on the surface of cells depends on the molecules’ chemical potential. However, measuring this potential, and how it varies with protein-to-protein distance, has been challenging. Here, we present a method we call hydrodynamic trapping that can achieve this. Our method uses the focused liquid flow from a micropipette to locally accumulate molecules protruding above a lipid membrane. The chemical potential, as well as information about the dimensions of… CONTINUE READING
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Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Label-free measurements of the diffusivity of molecules in lipid membranes.

  • Chemphyschem : a European journal of chemical physics and physical chemistry
  • 2014
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2017

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