Hydrodynamic properties of the beta-adrenergic receptor and adenylate cyclase from wild type and varient S49 lymphoma cells.

Abstract

Cell membranes from clones of cultured S49 mouse lymphoma cells were incubated with [*2511iodohydroxybenzyipindolol, a specific, high affinity ligand for the /3-adrenergic receptor, and guanyl-5’-yl imidodiphosphate, which activates adenylate cyclase irreversibly. Membranes were then solubilized with 0.1% Lubrol PX, and hydrodynamic properties of the ligand… (More)

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@article{Haga1977HydrodynamicPO, title={Hydrodynamic properties of the beta-adrenergic receptor and adenylate cyclase from wild type and varient S49 lymphoma cells.}, author={T. Haga and Kazunori Haga and Alfred G. Gilman}, journal={The Journal of biological chemistry}, year={1977}, volume={252 16}, pages={5776-82} }